Studies published in “Molecular Cancer Research” show that MUC1-C suppresses the Crumbs 3 (CRB3) polarity factor

9/22/2016

These findings show that MUC1-C suppresses the Crumbs 3 (CRB3) polarity factor and regulates the HIPPO tumor suppressor pathway in human triple-negative breast cancer cells, supporting the notion that MUC1-C is an attractive target for the treatment of patients with this often refractory malignancy.