Studies reported in “Oncoimmunology” demonstrate that MUC1-C promotes the suppressive immune microenvironment in NSCLC and that targeting MUC1-C induces CD8+ T-cell activation and killing of tumor cells

​These findings identify a role for MUC1-C in suppression of T-cell activation in the NSCLC tumor microenvironment and show that MUC1-C is an important target for the immunotherapy of lung cancer.

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