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MUC1 is aberrantly overexpressed in colon cancers and is associated with invasion, metastases and a poor prognosis.
Xu F, Liu F, Zhao H, An G, and Feng G, Prognostic significance of mucin antigen MUC1 in various human epithelial cancers: a meta-analysis. Medicine (Baltimore), 2015. 94:e2286.
Byrd JC and Bresalier RS, Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev, 2004. 23:77-99.
Suzuki H, Shoda J, Kawamoto T, Shinozaki E, Miyahara N, Hotta S, Iizuka Y, Nakahara A, Tanaka N, Yanaka A, and Irimura T, Expression of MUC1 recognized by monoclonal antibody MY.1E12 is a useful biomarker for tumor aggressiveness of advanced colon carcinoma. Clin Exp Metastasissis, 2004. 21:321-9.
Niv Y, MUC1 and colorectal cancer pathophysiology considerations. World J Gastroenterol, 2008. 14:2139-41.
Lugli A, Zlobec I, Baker K, Minoo P, Tornillo L, Terracciano L, and Jass JR, Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. J Clin Pathol, 2007. 60:534-9.
Nakamori S, Ota DM, Cleary KR, Shirotani K, and Irimura T, MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma. Gastroenterology, 1994. 106:353-61.
Baldus SE, Monig SP, Hanisch FG, Zirbes TK, Flucke U, Oelert S, Zilkens G, Madejczik B, Thiele J, Schneider PM, Holscher AH, and Dienes HP, Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis(a) and sialyl-Lewis(x) antigens in colorectal adenocarcinoma. Histopathology, 2002. 40:440-9.
Duncan TJ, Watson NF, Al-Attar AH, Scholefield JH, and Durrant LG, The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer. World J Surg Oncol, 2007. 5:31.
Zeng Y, Zhang Q, Zhang Y, Lu M, Liu Y, Zheng T, Feng S, Hao M, and Shi H, MUC1 predicts colorectal cancer metastasis: A systematic review and meta-analysis of case controlled studies. PLoS One, 2015. 10:e0138049.
Byrd JC and Bresalier RS, Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev, 2004. 23:77-99.
Suzuki H, Shoda J, Kawamoto T, Shinozaki E, Miyahara N, Hotta S, Iizuka Y, Nakahara A, Tanaka N, Yanaka A, and Irimura T, Expression of MUC1 recognized by monoclonal antibody MY.1E12 is a useful biomarker for tumor aggressiveness of advanced colon carcinoma. Clin Exp Metastasissis, 2004. 21:321-9.
Niv Y, MUC1 and colorectal cancer pathophysiology considerations. World J Gastroenterol, 2008. 14:2139-41.
Lugli A, Zlobec I, Baker K, Minoo P, Tornillo L, Terracciano L, and Jass JR, Prognostic significance of mucins in colorectal cancer with different DNA mismatch-repair status. J Clin Pathol, 2007. 60:534-9.
Nakamori S, Ota DM, Cleary KR, Shirotani K, and Irimura T, MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma. Gastroenterology, 1994. 106:353-61.
Baldus SE, Monig SP, Hanisch FG, Zirbes TK, Flucke U, Oelert S, Zilkens G, Madejczik B, Thiele J, Schneider PM, Holscher AH, and Dienes HP, Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis(a) and sialyl-Lewis(x) antigens in colorectal adenocarcinoma. Histopathology, 2002. 40:440-9.
Duncan TJ, Watson NF, Al-Attar AH, Scholefield JH, and Durrant LG, The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer. World J Surg Oncol, 2007. 5:31.
Zeng Y, Zhang Q, Zhang Y, Lu M, Liu Y, Zheng T, Feng S, Hao M, and Shi H, MUC1 predicts colorectal cancer metastasis: A systematic review and meta-analysis of case controlled studies. PLoS One, 2015. 10:e0138049.
